منابع مشابه
Intracellular calcium signalling in Alzheimer’s disease
More than two decades ago, dysregulation of the intracellular Ca(2+) homeostasis was suggested to underlie the development of Alzheimer's disease (AD). This hypothesis was tested in numerous in vitro studies, which revealed multiple Ca(2+) signalling pathways able to contribute to AD pathology. It remained, however, unclear whether these pathways are also activated in vivo, in cells involved in...
متن کاملReceptor-mediated intracellular signalling: oscillations and waves of cytosolic calcium.
17. I’eralta. E. G., Ashkenazi, A., Window. J. W., Kamachandran, J. and Capon, 1). J. (1988) Nature (London) 334, 434-437 18. Cotecchia. S., Kobilka, H. K., Daniel, K. W., Nolan. K. 11.. I,apetina, E. Y., Caron, M. G., IAkowitz, K. J. and Kegan. J. W. (1990) J . Hiol. Chem. 265,63-69 19. Abdel-l,atif, A. A. (1991) Cell. Signalling 3, 371-385 20. Kasmussen, H. and Kasmussen, J. E. (1990) Curr. T...
متن کاملCalcium signalling
Cellular signalling mechanisms are designed to transmit information from the cell surface membrane to specific targets within the cell. Often, the information is transmitted by means of intracellular messengers, of which the calcium ion, Ca2+, is one of the most important. Indeed, Ca2+ operates throughout the life history of a typical cell: it triggers new life at fertilisation, it controls man...
متن کاملIntracellular Signalling: Chloroplast Backchat
Chloroplast-derived signals modulate expression of nuclear genes for chloroplast proteins. GUN1 has recently been identified as a chloroplast-localized pentatricopeptide repeat protein that integrates information from several different signalling pathways.
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Recent evidence suggests that multiple calcium-releasing messengers might be activated simultaneously to regulate patterns of intracellular calcium signalling. In this way, agonists might use different messenger cocktails to encode specific signals and target selected processes.
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1995
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)46058-7